ISSN 1662-4009 (online)

ey0019.5-2 | Novel treatments for rare skeletal disorders | ESPEYB19

5.2. Reiterative infusions of MSCs improve pediatric osteogenesis imperfecta eliciting a pro-osteogenic paracrine response: TERCELOI clinical trial

A Infante , B Gener , M Vazquez , N Olivares , A Arrieta , G Grau , I Llano , L Madero , AM Bueno , B Sagastizabal , D Gerovska , MJ Arauzo-Bravo , I Astigarraga , CI Rodriguez

Clin Transl Med. 2021 Jan;11(1):e265. Abstract: https://pubmed-ncbi-nlm-nih-gov.proxy.kib.ki.se/33463067/In brief: In order to explore safety, efficacy, and feasibility of repeated infusions of mesenchymal stem cells (MSCs) as a treatment for OI, two pediatric OI patients were treated with repeated infusions of HLA-matched MSCs. The patients tolerated the treatment well and ...